Status:

COMPLETED

Effect of Korean Red Ginseng on Central Blood Pressure in Patient With Essential Hypertension

Lead Sponsor:

Daegu Catholic University Medical Center

Collaborating Sponsors:

The Korean Society of Ginseng

Conditions:

Hypertension

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine Korean red ginseng (KRG)treatment could decrease central blood pressure in subjects with hypertension.

Detailed Description

Participants with hypertension who were treated with antihypertensive agents were randomly assigned to an active (KRG 2 g/day) or a placebo treatment group in a double-blind cross over manner. Partic...

Eligibility Criteria

Inclusion

  • Essential hypertension
  • diastolic blood pressure 100 mmHg or less and systolic blood pressure 160 mmHg or less

Exclusion

  • Secondary hypertension
  • Serum creatinin above 1.5 mg/dL
  • aspartate aminotransferase(AST) and alanine aminotransferaseALT above two times upper normal limits
  • Uncontrolled diabetes (Hb A1c \< 9%)
  • Acute myocardial infarction or coronary artery disease intervention within six months
  • Moderate to severe congestive heart failure
  • HIV positive
  • Immunocompromized host
  • Allergy to Korean red ginseng
  • Pregnancy or plan to pregnancy
  • Alcohol or drug abuse
  • Attend to other clinical trial within 12 weeks

Key Trial Info

Start Date :

May 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2014

Estimated Enrollment :

58 Patients enrolled

Trial Details

Trial ID

NCT02211352

Start Date

May 1 2012

End Date

July 1 2014

Last Update

August 7 2014

Active Locations (1)

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Daegu Catholic University Medical Center

Daegu, South Korea, 705-718