Status:
COMPLETED
To Enhance Cognition in Late Life Depression Using Transcranial Direct Current Stimulation
Lead Sponsor:
Centre for Addiction and Mental Health
Collaborating Sponsors:
Ontario Ministry of Health and Long Term Care
Conditions:
Cognition
Depression
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Late Life Depression (LLD) is a serious health problem which not only causes depressed mood but also results in impairments in memory and attention. These impairments are likely to be resistant to tre...
Detailed Description
tDCS is a non-invasive brain stimulation method that utilizes low intensity electrical current either to increase cortical excitability with an anodal electrode or to suppress cortical excitability wi...
Eligibility Criteria
Inclusion
- Women and men of any races or ethnicity
- Age 60 and above
- Major depressive disorder, single or recurrent per SCID DSM-IV criteria AND remission from that episode as defined by DSM IV-TR criteria for remission.
- Montgomery-Asberg Depression Rating Scale (MADRS) score less than 10.
- Ability to speak English fluently enough to complete all research assessments.
- Corrected visual ability to read newspaper headlines; hearing capacity to respond to a raised conversational voice
- Willingness and ability to provide consent
Exclusion
- DSM IV TR criteria for any dementia
- DSM IV TR criteria for life-time bipolar disorder, schizophrenia, schizoaffective disorder, or other psychotic disorders
- DSM IV TR criteria for any substance abuse or dependence within the past 6 months
- Presence of psychotic features or any other symptoms that would make the participant unable to participate in the study.
- Any medical contra-indications to tDCS.
- Electroconvulsive therapy in the last 6 months.
Key Trial Info
Start Date :
May 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2017
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT02212366
Start Date
May 1 2014
End Date
November 1 2017
Last Update
January 24 2018
Active Locations (1)
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1
Center for Addiction and Mental Health
Toronto, Ontario, Canada, M6J1H4