Status:

COMPLETED

Brain Mechanisms Underlying the Effect of the Motilin Receptor Agonist Erythromycin on Hunger in Normal Weight Subjects

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Collaborating Sponsors:

KU Leuven

Conditions:

Healthy Volunteers

Eligibility:

FEMALE

18-60 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to investigate the role of erythromycin, a prokinetic agent, on hunger, and the brain mechanism lying behind it.

Eligibility Criteria

Inclusion

  • Female only.
  • Age \> 18 and \< 60.
  • Body Mass Index (BMI) of 19-25 kg/m2 (no weight change of more than 5 kg in the past three months).
  • Not known to have any chronic medical illness or illnesses affecting the gastrointestinal, cardiovascular, or nervous systems, chronic pain or psychiatric disorder.
  • If female not known to be pregnant.
  • Not known to have any past upper gastrointestinal surgery.

Exclusion

  • Alcohol consumption \> 7 drinks / week
  • Major depression and chronic health conditions except controlled hypertension

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT02212821

Start Date

September 1 2014

Last Update

November 30 2016

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