Status:
COMPLETED
Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
Lead Sponsor:
American University of Beirut Medical Center
Conditions:
Obesity
Sleep Apnea
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to determine if Dexmedetomidine given at the end of surgery will reduce postoperative morphine consumption and improve postoperative quality of recovery as compared to mor...
Detailed Description
effect of Dexmedetomidine bolus on postoperative morphine requirements
Eligibility Criteria
Inclusion
- Body Mass Index \> 40 kg/m2 or BMI \> 35 kg/m2 with comorbid conditions such as hypertension, diabetes or sleep apnea
- American Society of Anesthesiologists class I or II
- Undergoing laparoscopic sleeve gastrectomy bariatric surgery
Exclusion
- Allergy to morphine or its derivatives
- Allergy to α-2 adrenergic agonists
- weight over 180 kg
- history of uncontrolled hypertension
- heart block greater than first degree
- prolonged QT interval
- clinically significant neurologic, cardiovascular, renal, hepatic, or gastrointestinal diseases
- received an opioid analgesic medication within a 24 h period prior to surgery
- history of alcohol, drug abuse or chronic opioid intake
- history of psychiatric disorder
- pregnant or breastfeeding.
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02213159
Start Date
July 1 2014
End Date
December 1 2015
Last Update
July 13 2016
Active Locations (1)
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1
American University of Beirut Medical Center
Beirut, Lebanon