Status:
COMPLETED
Effect of Anesthesia on Post-operative Delirium in Elderly Patients Undergoing Hip Fracture Surgery
Lead Sponsor:
Wenzhou Medical University
Collaborating Sponsors:
National Research Institute for Family Planning, China
Conditions:
Post Operative Delirium
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
The purpose of this study is evaluate postoperative delirium after general anesthesia and regional anesthesia in elderly patients undergoing hip fracture surgery. Our research hypotheses are: (1) regi...
Detailed Description
Postoperative delirium (POD) is an acute confusional state associated with changes in consciousness, arousal level and cognitive status. Elderly patients with hip fractures have the high incidence of ...
Eligibility Criteria
Inclusion
- older patient (≥65 years)
- patient with hip fracture and planned hip fracture surgery
- patient willing to complete this study.
Exclusion
- patient with multiple trauma or multiple fractures, pathological fractures, pelvic fractures, femur fractures
- contraindication (serious illness or medical conditions) for general anesthesia
- contraindication (infection at the site of needle insertion, coagulopathy, international normalized ratio \>1.4, platelet count \<80×109 litre-1, allergy to local anaesthetics and so on) for regional anesthesia;
- patient who cannot complete the preoperative mental tests (CAM and/or Mini-Mental State Examination (MMSE)) of this clinical trial
- patient known to susceptible to malignant hyperthermia
- known allergy or hypersensitivity to any drugs administered during this clinical trial
- previous participation in this clinical trial
- participation in another clinical trial within 4 weeks prior to selection
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2020
Estimated Enrollment :
950 Patients enrolled
Trial Details
Trial ID
NCT02213380
Start Date
September 1 2014
End Date
January 1 2020
Last Update
May 9 2024
Active Locations (13)
Enter a location and click search to find clinical trials sorted by distance.
1
The Second Hospital of Anhui Medical University
Hefei, Anhui, China, 230601
2
Tongji Hospital, Tongji Medical college
Wuhan, Hubei, China, 430030
3
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China, 330006
4
West China Hospital of Sichuan University
Chengdu, Sichuan, China, 610041