Status:
TERMINATED
Glucosamine Periodontal Adjunctive Therapy
Lead Sponsor:
Ain Shams University
Conditions:
Chronic Periodontitis
Eligibility:
All Genders
35-48 years
Phase:
EARLY_PHASE1
Brief Summary
This study is the first evidence based work evaluated the systemic use of glucosamine as an adjunctive therapy to closed mechanical debridement in chronic periodontitis. The use of glucosamine sulphat...
Detailed Description
Targeting the inflammatory response may be a rational approach to the medical treatment of chronic periodontitis. Glucosamine sulphate (GS) was proven to have anti-inflammatory actions with minimal si...
Eligibility Criteria
Inclusion
- good compliance with the plaque control instructions following initial therapy
- each subject contributed a single premolar or molar tooth with interproximal probing depth ≥ 5 mm and clinical attachment loss ≥ 4 mm
- teeth involved were all vital with score 0-1 mobility
- availability for the follow-up and maintenance program;
Exclusion
- no systemic diseases which could influence the outcome of therapy as evidenced by Burket's Oral Medicine health history questionnaire
- absence of periodontal treatment for the previous year
- absence of systemic medication or antibiotic treatment for the previous six months
- absence of a smoking habit.
- post menopausal, pregnant or breast feeding women were excluded from participating in the study. Patients with contraindications to glucosamine sulphate therapy e.g., hypersensitivity to any of the product's components or with inadequate compliance with the oral hygiene maintenance schedule were also excluded from the study.
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT02214095
Start Date
January 1 2012
End Date
February 1 2013
Last Update
August 12 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ainshams University
Cairo, Egypt, 11566