Status:
COMPLETED
Noninvasive Ventilation Bundle in Postoperative Respiratory Failure
Lead Sponsor:
West China Hospital
Conditions:
Respiratory Insufficiency
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The investigators assessed the efficacy and safety of this noninvasive Ventilation (NIV) bundle strategy compared with a conventional treatment in postoperative patients with ARF.
Detailed Description
This is a randomized, prospective, open-label study. Postoperative patients with ARF included in the study were randomly assigned to intervention group or conventional treatment group. In the interven...
Eligibility Criteria
Inclusion
- Postoperative patients with acute respiratory failure (ARF) were included in the study,who had to meet one of the following criteria
- Respiratory acidosis (arterial pH of 7.35 or less with PaCO2 of 45 mm Hg or more)
- Partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio less than 250
- Dyspnoea with respiratory rate \> 25 breaths/min or use of accessory respiratory muscles or paradoxical abdominal breathing
Exclusion
- Cardiac or respiratory arrest; loss of consciousness
- Facial trauma or surgery or deformity sufficient to preclude mask fitting
- Active upper gastrointestinal bleeding
- Haemodynamic instability or unstable cardiac arrhythmia
- Multiple organ failure
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
158 Patients enrolled
Trial Details
Trial ID
NCT02214368
Start Date
January 1 2013
End Date
November 1 2014
Last Update
August 18 2015
Active Locations (1)
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1
Department of Critical care medicine of West China Hospital
Chengdu, Sichuan, China, 610041