Status:

COMPLETED

Diagnostic Interest of Leukocyte Immunophenotyping Using Multiparameter 8-color Flow Cytometry in Heart Surgery

Lead Sponsor:

University Hospital, Limoges

Conditions:

Cardiac Surgery

Eligibility:

All Genders

18+ years

Brief Summary

In septic patients, Septiflux1 study identified immature granulocytes which may have a diagnostic and prognostic interest. However, with these preliminary results it is not possible to make a differen...

Detailed Description

Expression of CD10, CD16, CD24, CD64 on granulocytes, of CD14 and CD16 on monocytes and of CD3 on T lymphocytes. Flow cytometers will all be calibrated the same way using common reagents (known fluor...

Eligibility Criteria

Inclusion

  • Patient older than 18 years old
  • Patient undergoing planned heart surgery with cardiopulmonary bypass

Exclusion

  • Pregnancy,
  • progressive solid cancer,
  • HIV infection,
  • history of blood or inflammatory disease,
  • long-term immunosuppressive treatment,
  • urgent surgical intervention,
  • documented preoperative infection

Key Trial Info

Start Date :

November 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2014

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02216019

Start Date

November 1 2013

End Date

April 1 2014

Last Update

August 15 2014

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de Limoges - Service de réanimation polyvalente

Limoges, Limoges, France, 87042