Status:
COMPLETED
Glargine Insulin vs.Continuous Regular Insulin in Diabetic Surgical Patients Receiving Parenteral Nutrition (GLUCOSE-in-PN)
Lead Sponsor:
King Faisal Specialist Hospital & Research Center
Conditions:
Diabetic Patients With Gastrointestinal Cancer Undergoing Surgery and Receiving Parenteral Nutrition
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Hyperglycemia increases the risk of complications in surgical patients. Focus on poor glycemic control as a contributor to adverse outcomes in settings outside the intensive care unit (ICU) is often d...
Eligibility Criteria
Inclusion
- All adult diabetic patients undergoing abdominal surgery operated by the surgical oncology team at KFSH \& RC and required TPN therapy are possible subjects of the study.
Exclusion
- Patients receiving octreotide or immunosuppressive agents including corticosteroids.
- Recipient of \< 3 units of regular insulin per day via subcutaneous insulin sliding scale after the third day of TPN recipient.
- Patients with clinically relevant hepatic disease (\> three times normal AST and ALT on admission to the hospital) or impaired renal function (GFR \< 60 ml/min), history of diabetic ketoacidosis.
- Patients who get infected while on TPN as reflected with elevation of white blood cells and elevated temperature \> 37.5 C will be excluded as well.
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT02216799
Start Date
March 1 2013
End Date
August 1 2015
Last Update
February 25 2016
Active Locations (1)
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1
King Faisal Specialist Hospital & Research Centre
Riyadh, Riyadh Region, Saudi Arabia, 11211