Status:

COMPLETED

The Effect of Vitamin D Supplementation on HIV-associated Platelet Hyperreactivity

Lead Sponsor:

Universitas Padjadjaran

Collaborating Sponsors:

Radboud University Medical Center

Conditions:

Blood Platelet Disorders

Vitamin D Deficiency

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Platelets play pivotal role in atherosclerosis and acute cardiovascular events. Platelet hyperreactivity and increase platelet-monocyte aggregate (PMA) formation are found in HIV infected patients, wh...

Detailed Description

1. Study design A prospective intervention study. HIV-infected patients using ART and who come for follow-up at the Teratai HIV clinic will be asked to participate in the study. All study participants...

Eligibility Criteria

Inclusion

  • \>18 years
  • Treated with suppressive first-line ART for at least 12 months
  • Compliant to ART and procedures of Teratai clinic
  • No signs or symptoms

Exclusion

  • Use of aspirin or other platelet function inhibitors.
  • Any sign or symptom
  • Known active opportunistic infection
  • Active illicit drug users or any other comorbidity
  • History of failing ART or non-compliance.
  • Pregnancy

Key Trial Info

Start Date :

December 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT02217553

Start Date

December 1 2013

End Date

June 1 2014

Last Update

August 18 2014

Active Locations (1)

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Klinik Teratai Hasan Sadikin General

Bandung, West Java, Indonesia, 40161