Status:

COMPLETED

31P Magnetic Resonance Spectroscopy Fructose Study

Lead Sponsor:

Stephen Bawden

Collaborating Sponsors:

Biotechnology and Biological Sciences Research Council

Unilever R&D

Conditions:

Healthy

Eligibility:

MALE

18-30 years

Phase:

NA

Brief Summary

The purpose of this study is to determine the effects of an oral fructose challenge on liver adenosine triphosphate (ATP) reserves using 31P magnetic resonance spectroscopy (MRS) as a potential measur...

Detailed Description

This study uses 31P spectra acquired from the liver in healthy subjects following a fructose drink to monitor ATP levels. This is also related to baseline BMI, liver glycogen and liver lipid levels

Eligibility Criteria

Inclusion

  • Male
  • Age 18 - 30
  • BMI 20 - 27 kg/m\^2
  • Healthy

Exclusion

  • Smokers
  • Liver disease or Metabolic Disorders
  • Metal implants (not suitable for MRI)

Key Trial Info

Start Date :

March 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2013

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT02217605

Start Date

March 1 2011

End Date

December 1 2013

Last Update

August 15 2014

Active Locations (1)

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1

University of Nottingham

Nottingham, Nottinghamshire, United Kingdom, NG7 2RD