Status:
UNKNOWN
A Prospective Investigation of the VWF-ADAMTS 13 Axis in Acute Ischaemic Brain Injury (TIAs and Stroke).
Lead Sponsor:
University College, London
Conditions:
Stroke
Eligibility:
All Genders
18+ years
Brief Summary
In patients presenting with acute stroke or transient ischaemic attacks (TIA), von Willebrand factor related parameters, including VWF antigen, activity, FVIII:c and propeptides, ADAMTS13 levels and V...
Eligibility Criteria
Inclusion
- Patients aged \>18 years of age presenting within 9 hours of onset of symptoms will be recruited from the hyperacute stroke unit at UCLH.
- Patients in whom stroke has been excluded or in whom intracerebral haemorrhage has been diagnosed are to be included as 'controls'. The definitive diagnosis will not be immediately obvious at presentation.
- Written consent will be obtained from patients or their nearest relative, particularly in patients with aphasia/dysphasia.
Exclusion
- Patients \<18 years old
- Patients with systemic vasculitis or active malignancy will be excluded.
- Patients not wishing to participate
Key Trial Info
Start Date :
December 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT02219035
Start Date
December 1 2014
Last Update
August 18 2014
Active Locations (1)
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1
UCLH
London, United Kingdom