Status:
UNKNOWN
The Influence of Partial Remission Phase of Type 1 Diabetes on Patient Outcome
Lead Sponsor:
Poznan University of Medical Sciences
Conditions:
Diabetes Mellitus Type 1
Remission of Type 1 Diabetes
Eligibility:
All Genders
18-35 years
Brief Summary
Natural course of diabetes mellitus involves gradual reduction of β cell mass within islets of Langerhans in the pancreas. Symptoms of diabetes present when the mass of insulin-producing cells reaches...
Detailed Description
Natural course of diabetes mellitus involves gradual reduction of β cell mass within islets of Langerhans in the pancreas. Symptoms of diabetes present when the mass of insulin-producing cells reaches...
Eligibility Criteria
Inclusion
- Newly diagnosed type 1 diabetes according to ADA (American Diabetes Association) 1997 criteria.
- Age 18-35 years
- Education with regard to intensive functional insulin therapy at the time of diagnosis
- Patient consent to participation in the study
Exclusion
- Acute inflammation (serum C-reactive protein concentration (hsCRP) \>10mg/L, leukocytosis \>15x109/L, erythrocyte sedimentation rate (OB) \>30 mm/h)
- Laboratory signs of liver damage: alanine and aspartate aminotransferase elevated 2-fold over the upper limit of normal range
- History of other chronic diseases (e.g. asthma, neoplastic diseases, liver cirrhosis)
- Other autoimmunological diseases other than diabetes
- Not confirming type 1 diabetes after obtaining results of autoantibodies
Key Trial Info
Start Date :
January 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2015
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT02220257
Start Date
January 1 2012
End Date
December 1 2015
Last Update
August 19 2014
Active Locations (1)
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1
Franciszek Raszeja Hospital; Poznan University of Medical Science
Poznan, Greater Poland Voivodeship, Poland, 60-834