Status:

COMPLETED

3-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals

Lead Sponsor:

Fundación Marques de Valdecilla

Collaborating Sponsors:

Centro de Investigación Biomédica en Red de Salud Mental

Instituto de Investigación Marqués de Valdecilla

Conditions:

Schizophrenia

Schizophrenia Relapse

Eligibility:

All Genders

15-60 years

Phase:

NA

Brief Summary

This open-label, non-randomized, prospective study will evaluate the risk of symptoms recurrence during the three years after antipsychotic discontinuation in a sample of functionally recovered first-...

Eligibility Criteria

Inclusion

  • Individuals included in the First Episode Psychosis Clinical Program (PAFIP) at the University Hospital Marqués de Valdecilla (Santander, Spain).
  • A minimum of 18 months on antipsychotic treatment.
  • Meeting clinical remission criteria for at least the 12 months prior to inclusion.
  • Meeting the functional recovery criteria for at least the 6 months prior to inclusion.
  • Stabilized at the lowest effective doses for at least the 3 months prior to inclusion.

Exclusion

  • Meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for drug dependence.
  • Meeting DSM-IV criteria for mental retardation.
  • Having a history of neurological disease or head injury.

Key Trial Info

Start Date :

July 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2014

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT02220504

Start Date

July 1 2004

End Date

July 1 2014

Last Update

March 14 2017

Active Locations (1)

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University Hospital Marques de Valdecilla

Santander, Cantabria, Spain, 39008