Status:

UNKNOWN

The Effect of Low-frequency rTMS on Motor Function in PD Patients With Freezing of Gait

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Conditions:

Parkinson's Disease

Eligibility:

All Genders

50-89 years

Phase:

NA

Brief Summary

This study is a double blind comparative study examining the effectiveness of the rTMS treatment on Freezing of Gait (FOG) phenomenon in patients with Parkinson's disease. We hypothesize that treatmen...

Detailed Description

A course of low-frequency repetitive transcranial magnetic stimulation (rTMS) delivered over the supplementary motor area (SMA) improves motor symptoms in patients with Parkinson's disease (PD). The ...

Eligibility Criteria

Inclusion

  • Idiopathic Parkinson's disease (PD), as diagnosed by a neurologist.
  • The mini-mental state examination questionnaire score above 24 points.
  • Suffer from a disabling phenomenon called Freezing of Gait (FoG) (Freezing Of Gait questionnaire score\> = 10)
  • Negative responses to the Preliminary Safety Magnetic Stimulation Treatment questionnaire.

Exclusion

  • Other neurological or psychiatric disorders.
  • Severe personality disorder.
  • High Blood Pressure.
  • History of epilepsy, seizures or convulsions.
  • History of epilepsy or convulsions in first-degree relatives.
  • History of head injury or stroke.
  • Metal remains of the skull or inside the brain (outside the oral cavity).
  • Surgeries including metallic implants or known history of metal particles in the eye, pacemakers, hearing devices transplantation, or medical pumps.
  • Current history of migraines for the last six months.
  • A history of drug or alcohol abuse
  • Other medical research in the time to experiment or three months ahead. -

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2016

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT02221544

Start Date

September 1 2014

End Date

December 1 2016

Last Update

August 20 2014

Active Locations (1)

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Tel Aviv Sourasky Medical Center

Tel Aviv, Israel, 64239