Status:
UNKNOWN
Evaluation of the High Dose Vitamin D3 Supplementation Effect and Influence of Polymorphism VDR Gene on Oxidative Stress and Inflammatory Process in Elderly
Lead Sponsor:
Federal University of Paraíba
Conditions:
Disorder of Aging
Eligibility:
FEMALE
60-90 years
Phase:
PHASE2
Brief Summary
A vitamin D3 high dose would act as an antioxidant and anti-inflammatory improving markers of oxidative stress and inflammation in the elderly. Seniors exhibiting polymorphism in the VDR gene would be...
Detailed Description
The high prevalence of hypovitaminosis D in the elderly can be identified as a risk factor for developing cardiovascular disease and consequent increase in oxidative stress and chronic inflammation. P...
Eligibility Criteria
Inclusion
- Aged 60 years; diagnosis of failure / vitamin D, preserved cognitive status, disability accepting participate and are not included in any of the exclusion criteria
Exclusion
- excluded from the study in the elderly using vitamin D supplements; anticonvulsant drugs or for the treatment of HIV / AIDS; diagnosis of type I diabetes mellitus, nephrotic syndrome, acute or chronic renal failure, liver disease, hypothyroidism, hyperthyroidism, history of cerebrovascular accident (CVA) or acute myocardial infarction (AMI) Vascular past 6 months and chronic consumptive diseases, alcoholic or smoker chronic.
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2015
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT02222649
Start Date
July 1 2014
End Date
September 1 2015
Last Update
March 6 2015
Active Locations (1)
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1
Program for Attention to Elderly, belonging to the Municipality of João Pessoa
João Pessoa, Paraíba, Brazil