Status:

COMPLETED

Evaluation of an Investigational Multifocal Lens

Lead Sponsor:

Johnson & Johnson Vision Care, Inc.

Conditions:

Presbyopia

Eligibility:

All Genders

40-70 years

Phase:

NA

Brief Summary

The purpose of this study is to test the performance of an investigational multifocal test soft contact lens.

Eligibility Criteria

Inclusion

  • The subjects were required to have read, understand, and signed the Statement of Informed Consent and receive a fully executed copy of the form.
  • The subject must appear able and willing to adhere to the instructions set forth in this clinical protocol.
  • Between 40 and 70 years of age.
  • Subjects must own a wearable pair of spectacles, if required for their distance vision.
  • Be an adapted soft contact lens wearer in both eyes (i.e. worn lenses a minimum of 2 days per week for at least 8 hours per wear day, for 1 month of more duration)
  • Already be wearing a presbyopic contact lens correction (e.g., reading spectacles over contact lenses, multifocal or monovision contact lenses, etc.) or if not respond positively to at least one symptom on the "Presbyopic Symptoms Questionnaire"\*
  • The subject's vertex corrected spherical equivalent distance refraction was required to be in the range +3.50 to -5.75 in each eye.
  • Refractive cylinder ≤ -0.75 D in each eye.
  • ADD power in the range +0.75 D to +2.50 D in each eye.
  • Best corrected visual acuity of 20/20-3 or better in each eye.

Exclusion

  • Currently pregnant or lactating (subjects who became pregnant during the study were discontinued).
  • Any ocular or systemic allergies that may have contraindicated contact lens wear.
  • Any ocular or systemic disease, autoimmune disease, or use of medication, that may have contraindicated contact lens wear.
  • Any ocular abnormality that may have interfered with contact lens wear.
  • Use of any ocular medication, with the exception of rewetting drops.
  • Any previous intraocular surgery (e.g., radial keratotomy, PRK, LASIK, etc.).
  • History of herpetic keratitis.
  • History of binocular vision abnormality or strabismus.
  • Any infectious disease (e.g., hepatitis, tuberculosis) or a contagious immunosuppressive disease (e.g., HIV).
  • History of diabetes.
  • Participation in any contact lens or lens care product clinical trial within 30 days prior to study enrollment.
  • Any Grade 3 or greater slit lamp findings (e.g., edema, corneal neovascularization, corneal staining, tarsal abnormalities, conjunctival injection) which may contraindicate contact lens wear.
  • Any ocular infection or inflammation.
  • Any corneal distortion or irregular cornea.

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2014

Estimated Enrollment :

371 Patients enrolled

Trial Details

Trial ID

NCT02223754

Start Date

August 1 2014

End Date

November 1 2014

Last Update

June 19 2018

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Montgomery, Alabama, United States, 36109

2

Mission Viejo, California, United States, 92691

3

Jacksonville, Florida, United States, 32205

4

Jacksonville, Florida, United States, 32250