Status:

COMPLETED

Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral Sclerosis

Lead Sponsor:

University of North Carolina, Chapel Hill

Conditions:

ALS

Eligibility:

All Genders

18-99 years

Brief Summary

The purpose of this research study is to discover and quantitate the differences in post-translational modifications found in the Cu, Zn superoxide dismutase (SOD1) of patients with amyotrophic latera...

Detailed Description

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease in which mutations in human Cu, Zn Superoxide Dismutase (SOD1) have been identified as a cause of familial ALS (FALS) cas...

Eligibility Criteria

Inclusion

  • SALS patients
  • SOD1 associated FALS patients
  • Healthy control

Exclusion

  • none

Key Trial Info

Start Date :

August 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 16 2018

Estimated Enrollment :

21 Patients enrolled

Trial Details

Trial ID

NCT02228915

Start Date

August 1 2014

End Date

October 16 2018

Last Update

October 17 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UNC Neurology ALS clinic

Chapel Hill, North Carolina, United States, 27599