Status:

COMPLETED

Effect of Chronic Intranasal Oxytocin Administration on Sexual Function in Pre- and Postmenopausal Women

Lead Sponsor:

Medical University of Vienna

Collaborating Sponsors:

Leadiant Biosciences, Inc.

Conditions:

Female Sexual Dysfunction

Eligibility:

FEMALE

40-70 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine whether intranasal oxytocin is effective in comparison to placebo in improving female sexual dysfunction in pre- and postmenopausal women.

Eligibility Criteria

Inclusion

  • Willingness to attempt sexual intercourse and/ or masturbation at least two times per week
  • Ongoing relationship for at least 3 months
  • Female subjects aging 40 years and more, Male subjects must be older than 18
  • The participation in this study should be of free choice to male partners
  • Willingness to perform a pregnancy test every month (for pre-menopausal subjects)
  • Willingness to use contraception during the study period (for pre-menopausal subjects)
  • Normal findings in the urogenital tract unless the investigator considers an abnormality to be clinically irrelevant
  • Normal laboratory values unless the investigator considers an abnormality to be clinically irrelevant
  • Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant

Exclusion

  • Primary sexual dysfunction
  • sexual abuse
  • severe psychiatric diseases
  • untreated conditions and medication intake with associated reduction of sexual function.
  • In male partners: any severe andrological or related medical problem.

Key Trial Info

Start Date :

June 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2013

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT02229721

Start Date

June 1 2012

End Date

October 1 2013

Last Update

September 1 2014

Active Locations (1)

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Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

Vienna, Vienna, Austria, 1090