Status:

COMPLETED

Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

Pr Joel COSTE, Hôpital Hôtel Dieu - Unité de Bio Statistiques et Epidémiologiques, Paris

URC-CIC Paris Descartes Necker Cochin

Conditions:

COPD (With - Without Rehabilitation)

Diffuse Interstitial Lung Diseases

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is the psychometric validation of a self-administered dyspnea questionnaire, usable in clinical practice in order to assess dyspnea and its impact on patients with chronic re...

Detailed Description

Dyspnea is a cardinal Respiratory symptom. According to the ATS dyspnea is the term used to characterize a subjective experience of breathing discomfort, covering qualitatively distinct sensations of...

Eligibility Criteria

Inclusion

  • 1\) Sample1: COPD GOLD / ATS \> 2 without major co-morbidity
  • Sample 1A: n = 50: group of patients with no change in usual care and no acute event (evaluation of reproducibility)
  • Sample1B: n = 60: patients assessed before and after a qualifying period of pulmonary rehabilitation
  • 2\) Sample 2 (n = 30): diffuse interstitial lung diseases Criteria: Pulmonary Fibrosis: Idiopathic or nonspecific interstitial lung diseases (NILD) according to international criteria (ATS), sarcoidosis with parenchymal lesions (old classification stage II and III), and exceptionally alveolar proteinosis.
  • 3\) Sample 3 (n = 30) primary or secondary arterial pulmonary hypertension (post embolic .....).
  • 4\) Sample4 (n = 30): Adult with Cystic fibrosis.
  • 5\) patient with stable Status (no exacerbation for at least one month)

Exclusion

  • 1\) Patient under 18 years
  • 2\) Inability to fill in questionnaires
  • 3\) Other respiratory disease
  • 4\) left symptomatic heart failure
  • 5\) Obesity with a BMI\> 35 kg/m2
  • 6\) Inability to perform PFT (Pulmonary Function Testing)
  • 7\) Pregnant or breastfeeding woman
  • 8\) Patient unable to consent
  • 9\) Lack of social insurance coverage
  • 10\) Patient in exclusion period because of another protocol

Key Trial Info

Start Date :

March 16 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 30 2015

Estimated Enrollment :

199 Patients enrolled

Trial Details

Trial ID

NCT02229994

Start Date

March 16 2010

End Date

December 30 2015

Last Update

November 20 2025

Active Locations (1)

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Service de Pneumologie AP-HP, Hôpitaux Universitaires Paris Centre

Paris, France, 75006