Status:
COMPLETED
High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease
Lead Sponsor:
University of Nevada, Las Vegas
Conditions:
Parkinson's Disease
Eligibility:
All Genders
45-85 years
Phase:
PHASE2
Brief Summary
Several animal and human epidemiologic studies have provided evidence that exercise may be neuroprotective in Parkinson's disease (PD). Exercise may forestall diagnosis and, in the case of those who h...
Eligibility Criteria
Inclusion
- Neurologist-diagnosed idiopathic PD based on the UK PD brain bank criteria
- Aged 45-85
- Hoehn and Yahr stages 1-3 (mild to moderate PD)
- Participants do not anticipate a change in medication or surgical procedures in the next 8 months of the trial (2 months for the trial and 6 for the follow-up)
- Clearance from primary care physician to participate in the trial
- Must be stable on PD medication and DBS for 3 months prior to trial
Exclusion
- Poorly controlled or unstable cardiovascular disease that precludes participation in exercise
- Moderate-to-severe dementia using the Montreal Cognitive Assessment (MoCA). We will exclude participants with a MoCA cut off score of \<26/30. This cut off value has excellent sensitivity (90%) and specificity (75%).
- Inability to stand or walk for more than 10 minutes
- Other significant disorders that would limit endurance exercise participation (i.e., osteoarthritis, stroke, respiratory problems, traumatic brain injury, neuromuscular disease, pain)
- Already participating in a regular, vigorous exercise program (3X/week or more of \>60% estimated maximum heart rate)
- Participants will be excluded from the trial if they are taking any medications that interfere with heart rate response to exercise
Key Trial Info
Start Date :
August 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT02230267
Start Date
August 1 2014
End Date
December 1 2015
Last Update
May 12 2016
Active Locations (1)
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1
University of Nevada, Las Vegas
Las Vegas, Nevada, United States, 89154