Status:

COMPLETED

Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function

Lead Sponsor:

Medical Center Alkmaar

Conditions:

Colon Cancer

Eligibility:

All Genders

60-80 years

Phase:

PHASE4

Brief Summary

Ideally, the postoperative inflammatory response is part of a well-orchestrated mechanism that contributes to tissue healing and rapid recovery. An exaggerated uncontrolled inflammatory response, howe...

Eligibility Criteria

Inclusion

  • Patients (male or female) undergoing elective laparoscopic surgery for colon cancer
  • Age between 60 and 80 years
  • BMI between 20 kg/m2 and below 30 kg/m2
  • Written informed consent

Exclusion

  • Participation in or having participated in another clinical trial within the previous 3 months
  • Indications for continuously use of anticoagulant medication and no possibility to stop these medication perioperatively, for example patients with an artificial heart valve
  • Pre-operative Hemoglobin\<5.0 mmol/L
  • Metastatic disease
  • Very poor peripheral venous access
  • Current history of inflammatory or infectious disease
  • The use of anti-inflammatory drugs
  • The use of thyroid medication
  • The use of fish oil products or fish consumption more than 2 times a week
  • Contra-indication for the use of Omegaven-Fresenius, including:
  • General contra-indications for parenteral nutrition
  • Allergy to fish or egg protein.

Key Trial Info

Start Date :

October 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT02231203

Start Date

October 1 2014

End Date

June 1 2016

Last Update

July 31 2018

Active Locations (1)

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Medical Center of Alkmaar

Alkmaar, North Holland, Netherlands