Status:
UNKNOWN
Innovation in Food Production Techniques to Improve Bioactive Content
Lead Sponsor:
University of East Anglia
Collaborating Sponsors:
Quadram Institute Bioscience
PepsiCo Global R&D
Conditions:
Bioavailability
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to establish to what extent innovations in food production techniques may facilitate retention of bioactive compounds in healthy individuals. The study has a single-blind...
Eligibility Criteria
Inclusion
- Men and women
- ≥ 18 years old
- Successful biochemical, haematological and urinalysis assessment at screening
Exclusion
- Current smokers, or ex-smokers ceasing \< 3 months ago
- Pregnant women, or those currently breast feeding
- Subjects with existing or significant past medical history of medical conditions likely to affect the study measures i.e. diabetes, hepatic, renal, digestive or cancer (excluding Basal-cell carcinoma) - to be judged by the study clinical advisor.
- Those unprepared to adhere to dietary restrictions for 3d preceding and during each assessment day.
- Parallel participation in another research project involving dietary intervention and/or sampling of biological fluids/material.
- Those on therapeutic diets or having experienced substantial weight loss (to be judged by clinical advisor) within 3 month of screening
- Taking dietary supplements containing flavonoids, isothiocyanates or carotenes (including multivitamins) (and unwilling to cease intake during, and 1 month preceding the trial) or unwilling to maintain existing intake of other supplements.
- Prescribed medications likely to affect ADME (absorption, distribution, metabolism, and excretion); medications to be assessed for suitability by the clinical advisor.
- Clinical advisor judged: abnormal biochemical, haematological or urinary results or measurements considered to be counter indicative for the study: including kidney and liver function, fasting glucose (especially if indicative of diabetes), lipid abnormalities, full blood count.
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2015
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02231502
Start Date
July 1 2014
End Date
January 1 2015
Last Update
November 11 2014
Active Locations (1)
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1
Norwich Medical School
Norwich, Norfolk, United Kingdom, NR4 7TJ