Status:
TERMINATED
Prospective,Randomized,Controlled Study to Assess Efficacy,Safety, and Tolerability of SLT vs. PLT in Patients With POAG
Lead Sponsor:
University Hospital, Geneva
Conditions:
Glaucoma and Ocular Hypertension
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A prospective, randomized, controlled study to assess efficacy, safety, and tolerability of selective laser trabeculoplasty vs. pattern laser trabeculoplasty in patients with open-angle glaucoma.
Detailed Description
This is a prospective, randomised, controlled study. Patients will be selected for this study who require bilateral laser trabeculoplasty for IOP control. Eyes will undergo a medication wash-out 4 wee...
Eligibility Criteria
Inclusion
- Diagnosis of open angle glaucoma (OAG) including pseudo-exfoliative and pigmentary glaucoma
- Patients requiring bilateral laser trabeculoplasty for IOP control
- Structural glaucomatous damage and/or documented glaucomatous VF damage (in the previous 12 months with mean defect (MD) \> 2.5 dB
- No or stable anti-glaucomatous drug therapy since at least 3 months. Able to undergo medication washout for 4 weeks prior to baseline 24-h IOP monitoring session.
- Aged ≥18 years, of either sex
- Not more than 6 diopters spherical equivalent on the study eye
- Have given written informed consent, prior to any investigational procedures
Exclusion
- Refractory glaucoma
- Patients having undergone ocular laser procedures (SLT, LPI) or intraocular surgery for the treatment of glaucoma.
- Corneal or conjunctival abnormality precluding contact lens adaptation
- Severe dry eye syndrome
- Patients with allergy to corneal anesthetic
- Patients with contraindications for silicone contact lens wear
- Patients not able to understand the character and individual consequences of the investigation
- Participation in other clinical research within the last 4 weeks
- Any other contra-indication listed in the CLS (SENSIMED Triggerfish) user manual
Key Trial Info
Start Date :
April 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT02231515
Start Date
April 1 2014
End Date
June 1 2016
Last Update
May 18 2023
Active Locations (1)
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1
Hôpitaux Universitaires de Genève, Ophtalmology Department
Geneva, Switzerland