Status:
COMPLETED
Simplified Rapid Hydration in Preventing CA-AKI Among Patients With Chronic Kidney Disease
Lead Sponsor:
Guangdong Provincial People's Hospital
Collaborating Sponsors:
Peking University First Hospital
Fudan University
Conditions:
Chronic Kidney Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
No well-defined protocols exist to guide fluid administration for prevention of contrast-associated acute kidney injury in high risk patients. The investigators will compare long term hydration at rou...
Detailed Description
No well-defined protocols exist to guide fluid administration for prevention of contrast-associated acute kidney injury in high risk patients undergoing coronary angiography. Long term hydration at ro...
Eligibility Criteria
Inclusion
- ≥18 years of age;
- Written informed consent;
- Candidates scheduled for coronary intervention (angiography and/or coronary intervention);
- Patients with chronic renal insufficiency, the baseline estimated glomerular filtration rate (eGFR) was 15-60 mL/min / 1.73 m²
- At least one risk factor (age\>75 years, medical history of diabetes mellitus or hypertension, congestive heart failure \[NYHA class \>II or history of acute pulmonary edema\]);
Exclusion
- End-stage renal failure or heart/renal transplantation;
- History of exposure to contrast medium or acute infectious diseases within 48 hours prior to the procedure;
- Acute decompensated heart failure;
- Left ventricular thrombus;
- Allergy to contrast agent;
- Pregnancy or lactation;
- Malignant tumour or life expectancy \<1 year;
- Pre-procedural receipt of NSAIDs (except Asprin), aminoglycosides, cyclosporine or cisplatin in the past 48 h;
- Severe valve disease or elective undergoing surgery.
Key Trial Info
Start Date :
April 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2021
Estimated Enrollment :
1002 Patients enrolled
Trial Details
Trial ID
NCT02232997
Start Date
April 1 2015
End Date
December 1 2021
Last Update
October 3 2022
Active Locations (1)
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1
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China, 501080