Status:
COMPLETED
Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Autism Spectrum Disorder
Eligibility:
All Genders
10-25 years
Brief Summary
Autism spectrum disorders (ASD) is a common childhood-onset, multi-factorial, highly heritable, clinically and genetically heterogeneous, neurodevelopmental disorder. Due to its high prevalence and se...
Detailed Description
Primary Aim: To investigate the neuropsychological, neuroimaging, social cognitive, and psychosocial outcomes at adolescence and young adulthood among children with ASD as compared to typically devel...
Eligibility Criteria
Inclusion
- ASD participants
- that they have a clinical diagnosis of autistic disorder or Asperger disorder defined by the DSM-IV and ICD-10 criteria, made by board-certificated child psychiatrists and who were clinically diagnosed with ASD confirmed by the ADI-R 7 years ago;
- their ages range from 10 to 25 (i.e., 3-18 years old at the first assessment);
- both parents are Han Chinese;
- who have complete clinical and behavioral data at the 1st assessment;
- participants and their parents consented to participate in this longitudinal study 7 years ago for complete assessments (3 visits of assessments) at follow-up.
- Inclusion Criteria for TD controls, who will be recruited either by school teachers or from the community, are that they are Han Chinese, consent to the study (if age \<18, parents, too) to complete all the assessments.
Exclusion
- For TD controls:
- comorbidity with DSM-IV-TR or DSM-5 diagnoses of ASD, ADHD, schizophrenia, schizoaffective disorder, delusional disorder, other psychotic disorder, organic psychosis, schizotypal personality disorder, bipolar disorder, depression, severe anxiety disorders or substance use;
- comorbidity with neurological or systemic disorders; and
- having a first degree relative who may have ASD based on family history method assessment.
Key Trial Info
Start Date :
January 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
523 Patients enrolled
Trial Details
Trial ID
NCT02233348
Start Date
January 1 2015
End Date
December 31 2019
Last Update
September 2 2021
Active Locations (1)
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1
National Taiwan Univeristy Hospital
Taipei, Taiwan