Status:
UNKNOWN
Mutation of the BTK Gene and Genotype-phenotype Correlation of Chinese Patients With X-Linked Agammaglobulinemia
Lead Sponsor:
Shanghai Children's Medical Center
Conditions:
Agammaglobulinemia, BTK
Eligibility:
MALE
1-18 years
Brief Summary
X-linked agammaglobulinemia (XLA) is a humoral primary immunodeficiency in which affected patients have very low levels of peripheral B cells and a profound deficiency of all immunoglobulin isotypes. ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Clinical diagnosis of XLA A.male patients with less than 2% CD19-positive B cells; B.recurrent bacterial infection; C.decreased or absent immunoglobulins in serum
- Exclusion Criteria for all groups:
- Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for XLA
Exclusion
Key Trial Info
Start Date :
September 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02234791
Start Date
September 1 2014
Last Update
September 9 2014
Active Locations (1)
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1
Shanghai Children'S Medical Center
Shanghai, Shanghai Municipality, China, 200127