Status:
COMPLETED
Criteria of Extubation Failure of Brain Injured Patients. Elaboration of a Prognostic Score.
Lead Sponsor:
University Hospital, Clermont-Ferrand
Conditions:
Brain Injury
Eligibility:
All Genders
15+ years
Brief Summary
Identification of criteria associated with extubation failure of brain injured patients. Elaboration of a prognostic score of extubation failure of brain injured patients.
Detailed Description
Prospective clinical study in ICU with brain injured ventilated patients eligible to extubation. Identification of clinical and biological criteria associated with failure of extubation. Elaboration...
Eligibility Criteria
Inclusion
- Adult brain injured patients ventilated eligible to discontinuation of mechanical ventilation
- Stable respiratory and hemodynamic conditions
- Ventilated patients for more than 48 hours
- Adequate gaseous exchange (SpO2 ≥ 92% and respiratory rate ≤ 35/min, FiO2 ≤ 40%, positive end-expiratory pressure ≤ 5 cmH2O, pressure support ≤ 8 cmH2O, tidal volume ≥ 7mL/kg
- Therapeutic extubation
Exclusion
- • Status epilepticus
- Cerebrospinal infection
- Patients under 15 years old
- Mechanical ventilation of \< 48 h
- Spinal cord injury
- Withdrawal of life support
Key Trial Info
Start Date :
June 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2015
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT02235376
Start Date
June 1 2013
End Date
September 1 2015
Last Update
October 15 2015
Active Locations (1)
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1
CHU de Clermont-Ferrand
Clermont-Ferrand, France, 63003