Status:

COMPLETED

Efficacy and Safety of Tazarotene Gel in Nail Psoriasis

Lead Sponsor:

Almirall, S.A.

Conditions:

Nail Psoriasis

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

The aim of this study is to determine the efficacy and safety of topical application of the gel compared to placebo in nail psoriasis.

Eligibility Criteria

Inclusion

  • Key inclusion criteria:
  • Mild to moderate nail psoriasis on at least one fingernail

Exclusion

  • Key exclusion criteria:
  • any other skin condition, with a potential to affect the nails or to interfere with evaluation of the disease;
  • history of hypersensitivity to retinoids or to other components of the trial medication
  • topical treatment of nails with antipsoriatics in the 4 weeks preceding the treatment phase;
  • systemic treatment of psoriasis within the three months before the treatment phase of the trial or during the trial
  • intralesional steroid injection before the treatment phase of the trial
  • phototherapy before the treatment phase of the trial;
  • any chronic infection or condition capable of interfering with the conduct of the trial;
  • evidence of drug or alcohol abuse;
  • symptoms of a clinically significant illness that may influence the outcome of the trial in the four weeks preceding the treatment phase of the trial;
  • participation in another clinical trial within the last 4 weeks prior to first treatment in this clinical trial;
  • pregnancy or nursing;

Key Trial Info

Start Date :

February 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2015

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT02235480

Start Date

February 1 2014

End Date

May 1 2015

Last Update

June 10 2015

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Investigational site 3

Berlin, Germany

2

Investigational site 4

Berlin, Germany

3

Investigational 2

Hamburg, Germany

4

Investigational site 1

Hamburg, Germany