Status:
UNKNOWN
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
Lead Sponsor:
Papworth Hospital NHS Foundation Trust
Conditions:
Right Coronary Artery Percutaneous Coronary Intervention
Right Ventricular Diastolic Dysfunction
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
The heart requires nutrients and oxygen carried in the blood to generate energy for healthy pump function. Blood is supplied via heart vessels called coronary arteries. When the arteries narrow the in...
Eligibility Criteria
Inclusion
- Age over 18
- Able to give informed consent
- Elective percutaneous intervention for a single vessel right coronary artery stenosis \>75%
- Normal right ventricular function
Exclusion
- Severe co-morbidity expected life (\<6months)
- Nicorandil or a GLP-1 receptor agonist or DPP-4 inhibitor use
- Women of child bearing age
- Myocardial infarction within the previous 3 months
- Previous coronary artery bypass graft to the RCA
- Significant known left to right shunt
- Permanent pacemaker
- Atrial fibrillation
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT02236299
Start Date
September 1 2014
Last Update
April 11 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Papworth Hospital NHS Foundation Turst
Cambridge, Cambridgeshire, United Kingdom, CB23 3RE