Status:
UNKNOWN
Rapid Intravenous Infusion of Mannitol Results in a Dipper-type Change in Stroke Volume Variation in Patients Undergoing Major Neurosurgery
Lead Sponsor:
First Affiliated Hospital, Sun Yat-Sen University
Conditions:
Craniotomy
Eligibility:
All Genders
18-65 years
Brief Summary
The purpose of this study is to observe the variation of Hemodynamics、lactic acid、base excess、peripheral vascular resistance and DO2 through FloTrac™/Vigileo™ system after rapid infusion mannitol in n...
Eligibility Criteria
Inclusion
- The inclusion criteria were: being aged between 16 and 70 years;
- with a body mass index of 18-25 kg/m2;
- with a physical status classified as ASA class I or II;
- and scheduled for elective craniotomy
Exclusion
- Any patient would be excluded from this study if the patient had complicating serious coagulopathy, hepatorenal insufficiency, aortic regurgitation, or cardiac arrhythmia;
- had a previous history of intra-aortic balloon counterpulsation;
- exhibited systolic blood pressure (SBP) ≥160 mmHg, diastolic blood pressure (DBP) ≥100 mmHg, or heart rate ≥ 100 bpm on operating room admission;
- or rejected to participate in this study.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2015
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT02237716
Start Date
June 1 2014
End Date
January 1 2015
Last Update
September 11 2014
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