Status:
COMPLETED
Evaluation of Fetoplacental Oxygenation With Functional MRI in Pregnant Women
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Intrauterine Growth Restriction
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the use of functional MRI in pregnant women as a non-invasive diagnostic tool to detect placental insufficiency and differentiate healthy fetuses from the intr...
Detailed Description
Intrauterine growth restriction (IUGR) is associated with important maternal and perinatal morbidity and mortality. IUGR is typically secondary to defective oxygenation, leading to placental insuffici...
Eligibility Criteria
Inclusion
- Major patient
- Patient with a singleton pregnancy
- Patient between 18 and 37 gestational weeks
- Informed consent signed by the patient
- Patient affiliated to a social security scheme (beneficiary or assignee) Specific criteria for patients with a eutrophic fetus
- Patient with fetal eutrophic on sonographic fetal weight estimation Specific criteria for patients with an IUGR-fetus Patient with a fetus presenting intra-uterine growth restriction diagnosed by ultrasound (\<5th percentile).
Exclusion
- Patient with the usual contra-indications for MRI
- Patient with an abdominal circumference\> 125 cm
- Patient with a multiple pregnancy
- Patient with placenta accreta or percreta
- Patient with a pregnancy after long history of infertility and medically assisted procreation
Key Trial Info
Start Date :
February 18 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 26 2019
Estimated Enrollment :
101 Patients enrolled
Trial Details
Trial ID
NCT02238301
Start Date
February 18 2015
End Date
September 26 2019
Last Update
September 8 2025
Active Locations (1)
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1
Necker - Enfants Malades Hospital (Assistance Publique des Hopitaux de Paris)
Paris, France, 75015