Status:

COMPLETED

Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception

Lead Sponsor:

Yale University

Collaborating Sponsors:

Anna Freud

Conditions:

Social Perception

Eligibility:

FEMALE

18-64 years

Phase:

EARLY_PHASE1

Brief Summary

The objective of this study is to investigate the effects of oxytocin on social behavior and brain activity using EEG and the event-related potential (ERP) technique. The value of EEG is its high temp...

Eligibility Criteria

Inclusion

  • Adults ages 18-64
  • Good medical health
  • Ability to understand and speak English

Exclusion

  • Pregnancy
  • Medical Illnesses: Moderate or severe acute or chronic medical illnesses (e.g. cardiac disease, diabetes, epilepsy, influenza).
  • Cardiovascular risk factors: History of hypertension with baseline blood pressure above 140 mm Hg (systolic) over 90 mm Hg (diastolic). Also any history of syncope and/or baseline blood pressure below 100 mm Hg (systolic).
  • CNS disease: Known history of brain abnormalities (e.g., neoplasms, subarachnoid cysts), cerebrovascular disease, infectious disease (e.g., abscess), other central nervous system disease, or history of head trauma which resulted in a persistent neurologic deficit or loss of consciousness \> 3 minutes.
  • Medication status: Individuals on stable doses of a neuroleptic and/or an antidepressant medication for at least the past 6 weeks will be allowed to participate in this study. The use of other psychotropic medications will not be allowed. Females taking contraceptive hormones will not be able to participate in the study.
  • A history of seizures or current use of anticonvulsants; history of head injury with loss of consciousness

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2015

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT02238379

Start Date

September 1 2014

End Date

December 1 2015

Last Update

January 17 2018

Active Locations (1)

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1

Yale Child Study Center

New Haven, Connecticut, United States, 06520