Status:

UNKNOWN

Use of Ventavis in Patients With Postembolic Residual Pulmonary Hypertension

Lead Sponsor:

Meshalkin Research Institute of Pathology of Circulation

Conditions:

Residual Pulmonary Hypertension

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

To assess the effectiveness of the synthetic analogue of prostacyclin in postembolic residual pulmonary hypertension.

Eligibility Criteria

Inclusion

  • Patients with pulmonary embolism after undergone surgical treatment (intravascular thrombolysis, catheter thrombus fragmentation)
  • Patients with preserved thromboembolism in the pulmonary circulation system and mean pressure in the pulmonary artery of more than 25 mm Hg

Exclusion

  • Patient did not sign the informed consent.
  • Mean pulmonary artery pressure after surgical treatment less than 25 mm Hg
  • Age above 75 years.
  • Patients with an increased risk of bleeding - including gastric ulcer and 12 duodenal ulcer in acute, hemorrhagic stroke.
  • Severe coronary artery disease (unstable angina, myocardial infarction within the last 6 months).
  • Acute heart failure or CHF IV in NYHA.
  • Severe arrhythmias.
  • Pregnancy, lactation.
  • The presence of severe diseases of other organ systems that may result in death during the first year after surgery.

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2016

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02238535

Start Date

September 1 2014

End Date

October 1 2016

Last Update

September 23 2015

Active Locations (1)

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1

State Research Institute of Circulation Pathology

Novosibirsk, Russia, 630055