Status:

COMPLETED

Role of the MET Oncogene in Human Colorectal Cancer - A Translational Study

Lead Sponsor:

Fondazione del Piemonte per l'Oncologia

Conditions:

Colorectal Cancer

Eligibility:

All Genders

18-80 years

Brief Summary

The MET oncogene is known to sustain the Trousseau's syndrome in murine experimental models, featuring association of carcinogenesis with a blood procoagulant disorder. MET is frequently overexpressed...

Eligibility Criteria

Inclusion

  • age \> or = 18;
  • age \< or = 80;
  • Clinical diagnosis of colorectal tumor by CT, MRI or endoscopy;
  • surgically resectable tumor;

Exclusion

  • Inclusion in other clinical protocols requiring administration of anticoagulant drugs;
  • Life expectancy \< 6 month;
  • Clinical diagnosis of thrombophilic condition by laboratory analysis;
  • Previously implanted Central Venous Catheter;
  • Previous or concomitant second neoplasia;
  • Clinical diagnosis of kidney, liver or heart failure;
  • Inflammatory markers alteration associated with disease unrelated to neoplasia (infection, connective tissue disease etc);
  • Severe hemostasis disorder;

Key Trial Info

Start Date :

October 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02238821

Start Date

October 1 2007

End Date

December 1 2016

Last Update

March 3 2017

Active Locations (1)

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Fondazione del Piemonte per l'Oncologia

Candiolo, TO, Italy, 10060