Status:
UNKNOWN
DPP-IV Inhibition Prior to Development of Diabetes in Patients With Cystic Fibrosis
Lead Sponsor:
Ram Weiss
Conditions:
Cystic Fibrosis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Cystic fibrosis related diabetes (CFRD) is a common co-morbidity in patients with CF. The underlying pathophysiology of cystic fibrosis related diabetes (CFRD) is still a matter of investigation. In a...
Detailed Description
The following proposal includes testing the utility of DPP-IV inhibition in adult patients with CF without CFRD. This will be achieved by a randomized double blind controlled trial of Saxagliptin 5 mg...
Eligibility Criteria
Inclusion
- Age greater than 18 years
- Diagnosis of CF
- No CFRD on baseline OGTT
- Normal kidney function
- No history of pancreatitis
- Able and willing to consent and participate
Exclusion
- Acute illness/exacerbation of CF associated lung disease
- Receiving immune-modulators following lung/pancreas transplant
Key Trial Info
Start Date :
June 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2016
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02239458
Start Date
June 1 2015
End Date
June 1 2016
Last Update
April 16 2015
Active Locations (1)
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1
Hadassah Ein Kerem/Har Hazofim
Jerusalem, Israel, 91120