Status:
WITHDRAWN
Non-Invasive Brain Stimulation for Medication-Resistant Auditory Hallucinations in Schizophrenia Patients
Lead Sponsor:
University of Minnesota
Conditions:
Auditory Hallucinations
Schizophrenia
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel neuromodulation approaches using tra...
Detailed Description
25% of schizophrenia (SZ) patients report chronic auditory hallucinations (AH) despite being on medication. Previous research proposed that hyperactivity of the left temporo-parietal cortex (11) and h...
Eligibility Criteria
Inclusion
- Current DSM-V-defined diagnosis of SZ or Schizoaffective Disorder as assessed by the Structured Clinical Interview for Axis I DSM-V Disorders (SCID-I/P)
- Ages 18-45
- Competent and willing to sign consent form
Exclusion
- Any serious neurological or endocrine disorder or any medical condition or treatment with neurological sequelae (i.e. stroke, tumor, loss of consciousness of more than 30 min, HIV)
- Diagnostic and Statistics Manual (DSM-V) criteria for mental retardation or axis I psychiatric disorder, subjects may have a lifetime but not current diagnosis of depression
- Primary current substance use disorder diagnosis on any substance except for caffeine or nicotine - nicotine use will be recorded but will not be an exclusion criterion
- Medical condition which requires treatment with a medication with psychotropic effects
- Significant risk of suicidal or homicidal behavior
- Documented loss of consciousness (LOC) for longer than 30 minutes or LOC with neurological sequelae
- History of electro-convulsive therapy
- Pregnancy
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02240446
Start Date
June 1 2013
End Date
December 1 2018
Last Update
July 20 2016
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55414