Status:
WITHDRAWN
Optimal Dose of i.v Oxycodone for Postoperative Pain After Laparoscopic Colorectal Surgery
Lead Sponsor:
Seoul National University Hospital
Conditions:
Pain
Eligibility:
All Genders
20-70 years
Phase:
PHASE3
Brief Summary
Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Eur...
Detailed Description
Oxycodone is known to be effective in pain control and has less sedative effect than morphine does. It has been described that distribution of cytochrome P450, which is associated with metabolism of o...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists class 1,2
- Expected surgical time between 2 - 6 hours
- Scheduled for laparoscopic colorectal surgery
Exclusion
- Severe dysfunction of liver, heart, kidney, or lung
- Cannot understand numeric rating scale of pain
- Known or suspected allergy to oxycodone
- Previous history of postoperative nausea or vomiting
- Medication of antidepressants
- Postoperative long-term ICU care or prolonged mechanical ventilatory support
- Chronic pain
- Drug abuser
- Hypersensitivity reaction to aspirin or NSAIDs
- Refuse to enroll
Key Trial Info
Start Date :
July 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02240602
Start Date
July 1 2015
End Date
December 1 2016
Last Update
June 16 2015
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea, 110-744