Status:
COMPLETED
Predicting Aortic Stenosis Progression by Measuring Serum Calcification Propensity
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Conditions:
Aortic Valve Sclerosis
Aortic Valve Stenosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Aortic stenosis is the most common valvular heart disease and an important public-health problem. Surgical or interventional aortic valve replacement are based on symptoms and measures of valvular and...
Detailed Description
Background Clinical Background Aortic stenosis is the most common valvular heart disease and an important public-health problem. It is present in approximately 25% of all adults aged \>65 years. Dec...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patient referred to routine clinical echocardiography
- Aortic sclerosis with or without stenosis
- Written informed consent
- Exclusion Criteria
- Age \<18 years
- Aortic valve replacement scheduled within 1 year after inclusion
- Any aortic valvular disease other than degenerative sclerotic, bi- or unicuspid valves
- Known disease with expected survival \<1 year
- Known malignant tumor
- Subvalvular obstruction (in left ventricular outflow tract) with mean pressure gradient \>10mmHg
Exclusion
Key Trial Info
Start Date :
September 30 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2017
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT02241109
Start Date
September 30 2014
End Date
February 28 2017
Last Update
March 30 2023
Active Locations (1)
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1
Dep. of Cardiology, Bern University Hospital
Bern, Switzerland, 3010