Status:
UNKNOWN
Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients
Lead Sponsor:
Fundación Cardiovascular de Colombia
Collaborating Sponsors:
Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS)
Conditions:
Aphasia, Broca
Eligibility:
All Genders
50-70 years
Phase:
PHASE3
Brief Summary
Aphasia is one of the most disabling complications in language production in patients with left hemisphere stroke. About 19% of patients who experience aphasia may have a spontaneously recovery after ...
Detailed Description
Some studies have reported that low frequency repetitive Transcranial Magnetic Stimulation in patients with ischemic stroke generates left modulation of cortical excitability by facilitating, and prom...
Eligibility Criteria
Inclusion
- Men and women age range from 50-70 years.
- School-level equal to or more than 5 years approved.
- Right hand dominance, determined through the Edinburgh Inventory (score above 40) .
- Ischemic stroke, at the territory of the left middle cerebral artery (MCA - Left).
- Aphasia diagnosis determined by the test for aphasia Boston.
- Patients who have previously received speech therapy
- Patients who gave their written informed consent
Exclusion
- Criteria defined by Wasserman, 1995 \[59, 60\] for rTMS:
- Pre-symptomatic diagnosis of stroke in more than one occasion.
- Diagnosis of neurodegenerative diseases such dementia and Parkinson's disease.
- Pre- Epilepsy diagnosis
- Diagnosis of Diabetes Mellitus Type I or II
- Diagnosis of liver disease or renal
- Diagnosis of Diseases-terminal to prevent tracking
- Diagnosis of psychiatric illnesses such as major depressive disorder (MDD) or other.
- Global cognitive impairment or previous diagnosis of dementia
- Visual or auditory deficit
- Patients with metal implants, cardiac pacemakers or drug infusion pumps.
Key Trial Info
Start Date :
August 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2017
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02241213
Start Date
August 1 2014
End Date
December 1 2017
Last Update
September 16 2014
Active Locations (1)
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1
Fundacion Cardiovascular de Colombia
Bucaramanga, Santander Department, Colombia, 0000