Status:

WITHDRAWN

Cell Therapy for Motor Neuron Disease/Amyotrophic Lateral Sclerosis

Lead Sponsor:

Neurogen Brain and Spine Institute

Conditions:

Amyotrophic Lateral Sclerosis

Eligibility:

All Genders

18-80 years

Phase:

PHASE1

Brief Summary

The effect of autologous bone marrow mononuclear cells on Motor Neuron Disease/Amyotrophic Lateral Sclerosis patients.

Eligibility Criteria

Inclusion

  • Patients with the diagnosis of definite Motor Neuron Disease/amyotrophic lateral sclerosis.
  • Age 18-80 years

Exclusion

  • HIV/HBV/HCV
  • Malignancies
  • Bleeding tendencies
  • Pneumonia
  • Renal failure
  • Severe liver dysfunction
  • Severe anemia \[hb \< 8\]
  • Any bone marrow disorder
  • Space occupying lesion in brain
  • Pregnancy and lactation
  • Other acute medical conditions/infections such as respiratory infection and pyrexia
  • left ventricular ejection fraction \< 25%
  • Patient on artificial ventilatory support

Key Trial Info

Start Date :

December 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2016

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT02242071

Start Date

December 1 2008

End Date

September 1 2016

Last Update

October 25 2018

Active Locations (1)

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1

Neurogen brain and spine institute

Navi Mumbai, Maharashtra, India, 400706