Status:

COMPLETED

Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen

Lead Sponsor:

Seoul National University Hospital

Conditions:

Ibuprofen

Remifentanil

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Postoperative hyperalgesia has been reported after intraoperative administration of small or high-dose remifentanil. Cyclooxygenase inhibitor exhibit preventive effects on the development of opioid-in...

Eligibility Criteria

Inclusion

  • Adult patients scheduled for elective pancreaticoduodenectomy

Exclusion

  • Patients with chronic pain
  • Patients with psychiatric disease
  • Patients with nonsteroidal antiinflammatory drugs allergy
  • Patients with renail dysfunction
  • History of drug addiction
  • Pregnant patient
  • Inability to use a PCA device

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT02243254

Start Date

July 1 2014

Last Update

November 18 2015

Active Locations (1)

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1

Seoul National University Hospital

Seoul, South Korea