Status:

COMPLETED

Manchester Antenatal Vascular Service

Lead Sponsor:

Manchester University NHS Foundation Trust

Collaborating Sponsors:

National Institute for Health Research, United Kingdom

Conditions:

Vascular Disease

Eligibility:

FEMALE

Brief Summary

25-30% of women with preexisting vascular disease (chronic hypertension/diabetes/obesity) will develop pre-eclampsia and or growth restriction. In addition, the frequency of stillbirths in this group ...

Eligibility Criteria

Inclusion

  • Women with preexisting vascular disease:
  • chronic hypertension BP ≥140/90 at ≤14 weeks
  • chronic hypertension requiring antihypertensive treatment ≤ 14 weeks
  • pre gestational diabetes with evidence of vascular complications (hypertension, nephropathy)
  • history of ischemic heart disease
  • previous early onset pre-eclampsia (delivery \< 32 weeks)
  • Obesity (BMI ≥ 40) with any history of hypertension or booking BP≥130/80

Exclusion

  • Women who do not meet the inclusion criteria

Key Trial Info

Start Date :

July 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2017

Estimated Enrollment :

750 Patients enrolled

Trial Details

Trial ID

NCT02244385

Start Date

July 1 2011

End Date

December 1 2017

Last Update

December 4 2018

Active Locations (1)

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1

Maternal & Fetal Health Research Centre, 5th Floor St Mary's Hospital

Manchester, United Kingdom, M13 9WL