Status:
COMPLETED
Effects of Maternal Folate and Folic Acid Supplementation on DNA Methylation in the Newborn Infant
Lead Sponsor:
Unity Health Toronto
Conditions:
Pregnancy
Maternal Nutrition
Eligibility:
FEMALE
18-45 years
Brief Summary
An overwhelming body of evidence of the protective effect of folic acid supplementation on neural tube defect affected pregnancies led to mandatory folic acid fortification in Canada in 1998. Folate i...
Eligibility Criteria
Inclusion
- singleton pregnancy
Exclusion
- celiac disease
- Crohn's disease
- irritable bowel disease (IBD)
- gastric bypass surgery
- use of antifolate medications
- banking umbilical cord blood
Key Trial Info
Start Date :
September 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
368 Patients enrolled
Trial Details
Trial ID
NCT02244684
Start Date
September 1 2010
Last Update
September 19 2014
Active Locations (1)
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1
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8