Status:
COMPLETED
Efficacy of Pergoveris in Aged IVF Patients
Lead Sponsor:
Vietnam National University
Conditions:
Infertility
Eligibility:
FEMALE
35-45 years
Phase:
NA
Brief Summary
To compare the efficacy between LH supplementation (Pergoveris) and non-LH supplementation (Follitropin alpha) in patients aged ≥ 35 years undergoing IVF treatment. Study hypothesis: Pergoveris (LH s...
Detailed Description
A randomized controlled single center study. Based on the difference of 19.1% in the clinical pregnancy rate between the two treatment groups, with and without LH supplementation, in a previous study...
Eligibility Criteria
Inclusion
- age ≥ 35 years
- body mass index \<28 kg/m2
- had ≤ 3 previous IVF attempts
- receiving a GnRH-antagonist protocol
- agreement to participate in the study, and to disclose any medical events to the investigator. The subject must be willing and able to comply with the protocol requirements for the duration of the study.
- have given written informed consent with the understanding that the subject may withdraw consent at any time
Exclusion
- participating in another interventional clinical trial
- PCOS or WHO group 1
- have uterine abnormalities
- have endocrine disorders such as hyperprolactinemia, thyroid disorders
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT02244866
Start Date
October 1 2012
End Date
June 1 2014
Last Update
December 25 2014
Active Locations (1)
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1
An Sinh Hospital
Ho Chi Minh City, Vietnam