Status:
COMPLETED
Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades
Lead Sponsor:
Uppsala University
Collaborating Sponsors:
Bengt Ihre Foundation
The Swedish Society of Medicine
Conditions:
Gastrointestinal Motility Disorder
Disturbance of Salivary Secretion
Eligibility:
All Genders
18-50 years
Phase:
PHASE1
Brief Summary
The aim is to elucidate how NO works in conjunction with other neurotransmitters to regulate the migrating motility complex (MMC). Twenty-two healthy volunteers should undergo water-perfused antroduod...
Detailed Description
Dysregulation of the cyclic motility pattern controlling propulsion during fasting, the migrating motor complex (MMC), can result in small intestinal bacterial overgrowth and symptoms of intestinal ob...
Eligibility Criteria
Inclusion
- Healthy volunteers 18-50 years of age
Exclusion
- Age \< 18, or \> 50 years
- Any disease
- Any medication
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT02245165
Start Date
June 1 2013
End Date
May 1 2014
Last Update
September 19 2014
Active Locations (1)
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1
Uppsala University
Uppsala, Uppsala County, Sweden, 75185