Status:

COMPLETED

Effect of CPAP Treatment on Glycemic Control in Gestational Diabetes: A Pilot Randomized-Controlled Trial

Lead Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Conditions:

Pregnancy

Sleep-disordered Breathing

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Clinical trial on effects of continuous positive airway pressure (CPAP) on glucose levels in pregnant patients with sleep-disordered breathing and gestational diabetes

Detailed Description

Gestational diabetes (GDM), defined as glucose intolerance that is first recognized during pregnancy, is associated with adverse maternal and fetal outcomes. Sleep-disordered breathing (SDB) is charac...

Eligibility Criteria

Inclusion

  • Pregnant women aged ≥ 18 y referred to the GDM clinic at the McGill University Health Centre
  • \>20 weeks and \<34 weeks gestational age at time of recruitment
  • Gestational diabetes
  • Sleep-disordered breathing (SDB)

Exclusion

  • Pre-gestational type 1 or type 2 diabetes
  • Multiple pregnancy
  • Conception by IVF
  • Prior treatment for SDB
  • severe medical illness
  • Severe SDB (AHI \>30) and Epworth Sleepiness Scale \>15 or oxygen desaturation index \>30 or sustained hypoxia \< 80%
  • Habitual sleep duration on average less than 5 hours/night (determined by actigraphy)
  • Cigarette smoking, alcohol consumption or illicit drug use

Key Trial Info

Start Date :

March 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2018

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT02245659

Start Date

March 1 2015

End Date

December 1 2018

Last Update

February 17 2021

Active Locations (1)

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McGill University Health Centre

Montreal, Quebec, Canada, H4A2Y3