Status:

COMPLETED

Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients

Lead Sponsor:

University of Florence

Conditions:

Obesity

Hypogonadism

Eligibility:

MALE

25-65 years

Brief Summary

The primary purpose of the study is to evaluate, in obese and hypogonadal patients eligible for bariatric surgery, the effect of testosterone replacement therapy in improving lower urinary tract sympt...

Detailed Description

Primary objective: \- Evaluation in obese and hypogonadal patients candidates for bariatric surgery of the effect of testosterone replacement therapy in improving the symptoms of LUTS (assessed using...

Eligibility Criteria

Inclusion

  • Male subjects
  • Age between 25 and 65 years
  • Obese men, candidate to a bariatric surgery (body mass index (BMI) is ≥40 kg/m2, or if their BMI is \>35 kg/m2 and they suffer from other life-threatening co-morbidities such as Type 2 Diabetes Mellitus, hypertension and cardiovascular disease)
  • Men with LUTS defined by: IPSS ≥ 8.
  • Evidence of a personally signed and dated informed consent

Exclusion

  • Bladder failure or Neurogenic bladder
  • LUT disease (Urethral stenosis, diverticula)
  • LUT surgery (Prostatectomy, bladder neck surgery, TURP)
  • Severe systemic disease
  • Previous or concomitant neoplasm
  • Unable to consistently and accurately complete the protocol
  • Abuse alcohol or drugs
  • Psychiatric disease

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2018

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT02248467

Start Date

May 1 2013

End Date

June 1 2018

Last Update

October 12 2018

Active Locations (1)

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Ambulatori Medicina della Sessualità e Andrologia

Florence, Italy

Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients | DecenTrialz