Status:
COMPLETED
Exercise and Colon Cancer
Lead Sponsor:
Abramson Cancer Center at Penn Medicine
Conditions:
Stage II Colon Cancer
Stage III Colon Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Despite the success of surgery and chemotherapy among people with colon cancer, 30-50% of patients develop recurrent disease. Physical activity has emerged as a potential lifestyle intervention to red...
Eligibility Criteria
Inclusion
- histologically confirmed TNM stage II-III CC;
- completed surgical resection and adjuvant chemotherapy (if applicable) within 1-24 months before entering the study;
- ≤120 min/wk of self-reported moderate or vigorous intensity physical activity using the Paffenbarger physical activity questionnaire;
- age ≥18 years;
- written physician approval;
- no additional surgery planned within the 6-month intervention (including colostomy reversal);
- ability to walk unaided for 6-minutes;
- no contraindications to exercise using the PA readiness questionnaire (PAR-Q), unless physician approves participation with specific knowledge of this contraindication.
Exclusion
- history of another primary invasive cancer (other than non-melanoma skin-cancer);
- evidence of metastatic CC (i.e., TNM M1);
- planning to receive any additional adjuvant chemotherapy;
- pregnant or breast feeding;
- unable to provide baseline blood sample;
- cardiac conditions, including the following:
- myocardial infarction or coronary revascularization procedure within prior 3 months;
- uncontrolled hypertension (systolic ≥180 mmHg or diastolic ≥100 mmHg);
- high-risk or uncontrolled arrhythmias;
- clinically significant valvular disease;
- decompensated heart failure;
- known aortic aneurysm;
- any other condition that may impede testing of the study hypothesis or make it unsafe to engage in the exercise program (determined by the investigative team).
Key Trial Info
Start Date :
December 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 15 2016
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT02250053
Start Date
December 1 2015
End Date
January 15 2016
Last Update
April 9 2020
Active Locations (1)
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1
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104