Status:
COMPLETED
Brain Stimulation and Hand Training in Children With Hemiparesis
Lead Sponsor:
University of Minnesota
Collaborating Sponsors:
Cerebral Palsy International Research Foundation
Foundation for Physical Therapy, Inc.
Conditions:
Pediatric Hemiparesis
Eligibility:
All Genders
8-21 years
Phase:
NA
Brief Summary
Hemiparetic cerebral palsy influences motor function in children during development and throughout their lifetime. The deficits one sees are the result both of the congenitally induced brain lesion an...
Detailed Description
We use single-pulse transcranial magnetic stimulation (TMS) to measure the location and strength of brain connections that control hand movements.
Eligibility Criteria
Inclusion
- Hemispheric Stroke or Periventricular Leukomalacia confirmed by most recent MRI or CT radiologic report with resultant congenital hemiparesis
- ≥ 10 degrees of active motion at the metacarpophalangeal joint
- Receptive language function to follow two-step commands as evidenced by performance on TOKEN test of intelligence
- No evidence of seizure activity within the last 2 years
- Presence of a motor evoked potential from at least the contralesional hemisphere if not both hemispheres
- Ages 8-21 years
- Able to give informed assent along with the informed consent of the legal guardian
- Children who have had surgeries, which may influence motor function eg- tendon transfer, will be included, yet surgical history will be documented and included in any publication within a participant characteristics table.
Exclusion
- Metabolic Disorders
- Neoplasm
- Epilepsy
- Disorders of Cellular Migration and Proliferation
- Acquired Traumatic Brain Injury
- Pregnancy
- Indwelling metal or incompatible medical devices
- Evidence of skin disease or skin abnormalities
- Botulinum toxin or Phenol block within \[six-months\] preceding the study
Key Trial Info
Start Date :
December 31 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 10 2017
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02250092
Start Date
December 31 2014
End Date
July 10 2017
Last Update
August 18 2020
Active Locations (2)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455
2
Gillette Children's Specialty Healthcare
Saint Paul, Minnesota, United States, 55101